Table 2 Comparing the result of MassARRAY and Sanger sequencing in 1,908 tests.

From: Screening of single nucleotide polymorphisms within HLA region related to hematopoietic stem cell transplantation using MassARRAY technology

Result of new method MassARRAY

Result of Sanger sequencing

Total

Variant allele

Reference allele

Variant allele

614

0

PPV = 614/(614 + 0)

 = 100%

Reference allele

13

1281

NPV = 1281/(13 + 1281)

 = 99.0%

 

Sensitivity = 614/(614 + 13) = 97.9%

Specificity = 1281/(1281 + 0) = 100%

 
  1. PPV: positive predictive values; NPV: negative predictive values.