Table 1 Characteristics of the studies considered for the analysis of single nucleotide polymorphism-exposure associations in the Japanese Consortium of Genetic Epidemiology Studies.

From: Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation

Phenotype

Source

Participants

Mean ± SD

Units

No. of SNPs

Variance explained, % (F-statistic)

Population

Fasting glucose levels

JPHC

3,537 Non-diabetic individuals

94.3 ± 10.1

mg/dL

34

2.48 (13.71)

Japanese

TMM

9,900 Non-diabetic individuals

88.2 ± 10.0

J-MICC

3,852 Non-diabetic individuals

94.4 ± 9.3

HbA1c

JPHC

8,207 Non-diabetic individuals

5.3 ± 0.4

%

43

1.22 (15.15)

Japanese

TMM

36,647 Non-diabetic individuals

5.5 ± 0.3

J-MICC

7,948 Non-diabetic individuals

5.4 ± 0.3

Fasting C-peptide levels

JPHC

1,666 Non-diabetic individuals

1.4 ± 0.5

ng/mL

17

1.04 (1.08)

Japanese

  1. HbA1c haemoglobin A1c, HERPACC the Hospital-based Epidemiologic Research Program at Aichi Cancer Center, J-MICC the Japan Multi-Institutional Collaborative Cohort, JPHC Japan Public Health Center, TMM the Tohoku Medical Megabank.