Figure 6

Apigenin has no effect on attenuation of hepatic lipid accumulation and atherosclerosis in NLRP3^−/−Ldlr^−/− mice fed a high-fat diet (HFD). (A) and (B). Plasma TG and TC levels in mice. (C) and (D). The content of TG and TC in mice livers. (E) and (F). Representative aortic root sections stained with Oil Red O, and quantification of aortic lesion areas. Data are presented as the mean ± SEM, ^*P < 0.05, ^**P < 0.01 for HFD mice versus HFD + APN 50 mice.