Table 4 Univarite analysis of risk factors in respiratory disease mortality.
 | Respiratory diseases including malignancy (n = 1263) | Respiratory diseases excluding malignancy (n = 437) | Malignant neoplasm of respiratory tract (n = 826) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Hazard ratio | 95% CI | p value | Hazard ratio | 95% CI | p value | Hazard ratio | 95% CI | p value | ||||
Sex (men) | 3.595 | 3.182 | 4.071 |  < 0.0001* | 3.780 | 3.069 | 4.689 |  < 0.0001* | 3.503 | 3.016 | 4.082 |  < 0.0001* |
Age (+ 1 year) | 1.106 | 1.095 | 1.118 |  < 0.0001* | 1.132 | 1.111 | 1.155 |  < 0.0001* | 1.094 | 1.081 | 1.108 |  < 0.0001* |
Body mass index (+ 1 kg/m2) | 0.959 | 0.943 | 0.976 |  < 0.0001* | 0.902 | 0.874 | 0.930 |  < 0.0001* | 0.989 | 0.968 | 1.009 | 0.2727 |
Waist circumference (+ 1 cm) | 0.999 | 0.993 | 1.005 | 0.8277 | 0.983 | 0.973 | 0.993 | 0.0011* | 1.008 | 1.000 | 1.015 | 0.0385* |
Systolic blood pressure (+ 1 mmHg) | 1.006 | 1.003 | 1.009 | 0.0004* | 1.002 | 0.997 | 1.008 | 0.3949 | 1.007 | 1.004 | 1.011 | 0.0002* |
Diastolic blood pressure (+ 1 mmHg) | 0.997 | 0.991 | 1.002 | 0.1773 | 0.986 | 0.978 | 0.995 | 0.0021* | 1.002 | 0.996 | 1.008 | 0.5788 |
Weight gain more than 10Â kg since age 20 | 0.927 | 0.813 | 1.055 | 0.2521 | 0.744 | 0.589 | 0.932 | 0.0097* | 1.039 | 0.884 | 1.217 | 0.6427 |
Exercise habit for more than 30Â min | 0.896 | 0.789 | 1.016 | 0.0878 | 0.663 | 0.534 | 0.834 | 0.0003* | 1.042 | 0.892 | 1.217 | 0.6004 |
Habit of walking and/or physical activity | 0.868 | 0.767 | 0.982 | 0.0241* | 0.718 | 0.581 | 0.886 | 0.0019* | 0.960 | 0.824 | 1.119 | 0.6015 |
Fast walking speed | 0.547 | 0.480 | 0.622 |  < 0.0001* | 0.308 | 0.239 | 0.391 |  < 0.0001* | 0.719 | 0.614 | 0.839 |  < 0.0001* |
Smoking history | 2.278 | 2.016 | 2.570 |  < 0.0001* | 1.265 | 0.987 | 1.601 | 0.0629 | 2.947 | 2.550 | 3.398 |  < 0.0001* |
Drinking habits | 1.142 | 1.020 | 1.278 | 0.0217* | 0.876 | 0.721 | 1.062 | 0.1768 | 1.314 | 1.142 | 1.513 | 0.0001* |
Adequate sleep | 1.366 | 1.168 | 1.606 |  < 0.0001* | 1.124 | 0.879 | 1.456 | 0.3567 | 1.536 | 1.256 | 1.896 |  < 0.0001* |
History of cerebrovascular diseases | 2.647 | 2.148 | 3.225 |  < 0.0001* | 3.335 | 2.407 | 4.504 |  < 0.0001* | 2.289 | 1.733 | 2.963 |  < 0.0001* |
History of cardiovascular diseases | 2.217 | 1.845 | 2.641 |  < 0.0001* | 2.632 | 1.961 | 3.462 |  < 0.0001* | 2.000 | 1.575 | 2.504 |  < 0.0001* |
History of chronic renal failure | 1.313 | 0.721 | 2.169 | 0.3496 | 2.341 | 1.064 | 4.394 | 0.0361* | 0.771 | 0.276 | 1.664 | 0.5455 |
History of anemia | 0.979 | 0.801 | 1.184 | 0.8288 | 1.096 | 0.788 | 1.484 | 0.5754 | 0.917 | 0.709 | 1.166 | 0.4893 |
Medication of hypertension | 1.555 | 1.386 | 1.741 |  < 0.0001* | 1.516 | 1.246 | 1.839 |  < 0.0001* | 1.575 | 1.367 | 1.812 |  < 0.0001* |
Medication of diabetes | 2.220 | 1.843 | 2.650 |  < 0.0001* | 3.435 | 2.621 | 4.430 |  < 0.0001* | 1.627 | 1.248 | 2.081 | 0.0005* |
Medication of dyslipidemia | 0.970 | 0.825 | 1.135 | 0.7098 | 0.898 | 0.673 | 1.175 | 0.4414 | 1.009 | 0.827 | 1.221 | 0.9247 |
Fasting blood glucose (+ 1 mg/dl) | 1.009 | 1.007 | 1.010 |  < 0.0001* | 1.009 | 1.006 | 1.012 |  < 0.0001* | 1.008 | 1.006 | 1.010 |  < 0.0001* |
Hemoglobin A1c (+ 1%) | 1.268 | 1.203 | 1.330 |  < 0.0001* | 1.316 | 1.211 | 1.416 |  < 0.0001* | 1.239 | 1.157 | 1.319 |  < 0.0001* |
Triglyceride (+ 1 mg/dl) | 1.000 | 1.000 | 1.001 | 0.1650 | 0.999 | 0.997 | 1.000 | 0.0431* | 1.001 | 1.000 | 1.002 | 0.0038* |
High density lipoprotein cholesterol (+ 1 mg/dl) | 0.979 | 0.975 | 0.983 |  < 0.0001* | 0.982 | 0.975 | 1.018 |  < 0.0001* | 0.978 | 0.973 | 0.983 |  < 0.0001* |
Low density lipoprotein cholesterol (+ 1 mg/dl) | 0.990 | 0.988 | 0.991 |  < 0.0001* | 0.987 | 0.984 | 0.990 |  < 0.0001* | 0.991 | 0.989 | 0.993 |  < 0.0001* |
Aspartate aminotransferase (+ 1 U/L) | 1.004 | 1.002 | 1.006 | 0.0002* | 1.005 | 1.002 | 1.007 | 0.0018* | 1.004 | 1.001 | 1.006 | 0.0271* |
Alanine aminotransferase (+ 1 U/L) | 0.996 | 0.991 | 0.999 | 0.0443* | 0.996 | 0.989 | 1.004 | 0.2793 | 0.996 | 0.990 | 1.001 | 0.0889 |
Hemoglobin (+ 1 g/dl) | 1.045 | 0.983 | 1.111 | 0.1578 | 0.931 | 0.837 | 1.038 | 0.1940 | 1.104 | 1.024 | 1.186 | 0.0097* |
Hematocrit (1%) | 1.015 | 0.993 | 1.037 | 0.1883 | 0.976 | 0.940 | 1.014 | 0.2168 | 1.032 | 1.006 | 1.059 | 0.0157* |
Red blood cell (+ 1 /μL) | 0.999 | 0.998 | 1.001 | 0.0588 | 0.998 | 0.996 | 1.002 | 0.0799 | 0.999 | 0.998 | 1.001 | 0.2835 |
Uric acid (+ 1 mg/dl) | 1.072 | 1.055 | 1.084 |  < 0.0001* | 1.071 | 1.041 | 1.090 | 0.0002* | 1.072 | 1.051 | 1.086 |  < 0.0001* |
Creatinine (+ 1 mg/dl) | 1.334 | 1.251 | 1.404 |  < 0.0001* | 1.388 | 1.269 | 1.482 |  < 0.0001* | 1.291 | 1.166 | 1.389 |  < 0.0001* |
Estimated glomerular filtration rate (+ 1 mL/min/1.73m2) | 1.000 | 0.997 | 1.004 | 0.9332 | 1.005 | 1.000 | 1.007 | 0.0427* | 0.996 | 0.992 | 1.001 | 0.1067 |
Urinary protein (positive) | 1.789 | 1.554 | 2.051 |  < 0.0001* | 2.310 | 1.845 | 2.867 |  < 0.0001* | 1.538 | 1.280 | 1.834 |  < 0.0001* |