Table 3 Logistic regression analysis of “sustained ROSC” associated with ESKD and other variables in OHCA patients.

From: Effect of end-stage kidney disease on the return of spontaneous circulation in Taiwanese adults with out-of-hospital cardiac arrest

 

Unadjusted model

† Adjusted model

OR

95% CI

P value

Adjusted OR

95% CI

P value

ESKD (Yes)

6.77

4.4, 10.66

 < 0.01*

9.45

3.83, 24.13

 < 0.01*

Sex (Male)

1.02

0.75, 1.39

0.92

1.34

0.71, 2.56

0.37

Age

0.99

0.98, 0.99

 < 0.01*

0.98

0.96, 0.99

 < 0.01*

Baseline comorbidities

 HTN

1.06

0.73, 1.53

0.77

0.42

0.17, 1.01

0.06

 DM

0.99

0.72, 1.35

0.93

0.46

0.22, 0.93

0.03*

 COPD

0.58

0.41, 0.82

 < 0.01*

1.33

0.62, 2.84

0.46

 CLD

0.89

0.52, 1.49

0.65

1.43

0.53, 3.67

0.47

 CKD

0.43

0.29, 0.64

 < 0.01*

1.11

0.48, 2.53

0.80

 PAOD

1.03

0.48, 2.11

0.94

1.05

0.29, 3.47

0.94

 Stroke

0.89

0.64, 1.23

0.48

0.77

0.37, 1.57

0.47

 IHD

3.26

2.13, 5.04

 < 0.01*

4.02

1.70, 9.76

 < 0.01*

 Cancer

0.48

0.34, 0.66

 < 0.01*

0.66

0.33, 1.29

0.24

Blood markers

 Albumin

0.98

0.61, 1.57

0.93

0.77

0.27, 2.15

0.62

 Hb

0.96

0.89, 1.03

0.22

0.85

0.72, 0.99

0.05*

 PLT

1.01

1, 1.01

 < 0.01*

1.01

1, 1.01

 < 0.01*

 Creatinine

1.05

0.95, 1.15

0.32

1.28

1.01, 1.67

0.05*

 Na

0.97

0.94, 0.99

0.02*

0.94

0.90, 0.97

 < 0.01*

 K

0.16

0.12, 0.21

 < 0.01*

0.16

0.11, 0.24

 < 0.01*

 CK

1

1, 1

0.01*

1

1, 1

0.42

 Troponin I

0.83

0.76, 0.90

 < 0.01*

0.91

0.84, 0.98

0.01*

 PH

15,123.23

3121, 85,308

 < 0.01*

1024.83

36, 31,201

 < 0.01*

 PCO2

0.94

0.93, 0.95

 < 0.01*

1

0.98, 1.01

0.69

 Lactate

0.98

0.97, 0.98

 < 0.01*

1

0.99, 1

0.35

 Ca

0.85

0.75, 0.97

0.02*

1.12

0.88, 1.44

0.36

ED treatment

 Electric shock

4.26

2.43, 7.75

 < 0.01*

1.49

0.44, 5.20

0.53

 7% NaHCO3

5.22

3.76, 7.30

 < 0.01*

10.79

5.81, 20.69

 < 0.01*

 Amiodarone

5.51

2.55, 13.26

 < 0.01*

2.20

0.46, 11.74

0.34

 Lidocaine

5.23

1.20, 35.83

0.04*

0.30

0.03, 3.74

0.33

  1. ROSC return of spontaneous circulation, ESKD end-stage kidney disease, COPD chronic obstructive pulmonary disease, CLD chronic liver disease, CKD chronic kidney disease, ED emergency department, PAOD peripheral artery occlusive disease, IHD ischemic heart disease, Hb hemoglobin, PCO2 partial pressure of carbon dioxide, NaHCO3 sodium bicarbonate.
  2. †Adjusted for sex, age, baseline comorbidities, all blood markers, and ED treatments. *P value < 0.05.
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