Figure 3 | Scientific Reports

Figure 3

From: Prosaposin PS18 reduces dopaminergic neurodegeneration in a 6-hydroxydopamine rat model of Parkinson’s disease

Figure 3

PS18 antagonized Meth and Tg-mediated apoptosis in rat primary dopaminergic culture. Representing photomicrographs demonstrate that Meth (1 mM) or Tg (500 nM) increased TUNEL in dopaminergic neuronal culture. PS18 (50 nM) significantly reduced TUNEL ( +) cell density (*p < 0.001, 1-way ANOVA + NK test). Scale bar = 50 μm.

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