Table 1 Clinical characters of all available affected individuals with ARR3 mutation.
From: The causal mutation in ARR3 gene for high myopia and progressive color vision defect
Subject no | Gender | Age (years) | Eye | Axial length (mm) | Refraction (DS) | Best corrected visual acuity | Color vision | Fundus morphologic findings |
|---|---|---|---|---|---|---|---|---|
II-2 | F | 56 | OD | 21.8 |  + 1.6 | NA | NA | Normal |
OS | 22.0 |  + 1.3 | NA | Normal | ||||
65 | OD | 21.78 |  + 2.25 | 20/30 | Color vision defect | Normal | ||
OS | 22.0 |  + 2.25 | 20/25 | Normal | ||||
II-3 | M | 68 | OD | 24.17 | NA | NA | Color vision blindness | Proliferative diabetic retinopathy, macular edema |
OS | 23.64 | NA | NA | Proliferative diabetic retinopathy, macular edema | ||||
III-1 | M | 35 | OD | 25.5 | − 3.8 | NA | Color vision defect | Normal |
OS | 25.3 | − 2.8 | NA | Normal | ||||
40 | OD | 25.6 | − 3.75 | 20/30 | Color vision defect | Normal | ||
OS | 25.4 | − 3.25 | 20/30 | Normal | ||||
III-4 | F | 35 | OD | 25.6 | − 10.1 | NA | NA | Conus |
OS | 26.2 | − 9.8 | NA | Conus | ||||
44 | OD | 25.49 | − 6.75 | 20/33 | Normal | Conus, tigroid | ||
OS | 26.33 | − 8.00 | 20/30 | Conus, tigroid | ||||
III-8 | F | 47 | OD | 28.77 | − 13.25 | 20/100 | Color vision defect | Tigroid, conus, Fuchs spot |
OS | 28.59 | − 13.25 | 20/60 | Tigroid, conus, Fuchs spot | ||||
III-11 | F | 40 | OD | 30.5 | − 24.3 | NA | NA | Tigroid, conus |
OS | 29.7 | − 21.9 | NA | Tigroid, conus | ||||
47 | OD | 30.99 | − 25.00 | 20/60 | Normal | Tigroid, conus | ||
OS | 30.00 | − 23.75 | 20/100 | Tigroid, conus, macular retinoschisis | ||||
III-15 | F | 46 | OD | 30.0 | − 18.5 | NA | NA | Tigroid, conus, Fuchs spot |
OS | 29.0 | − 16.4 | NA | Tigroid, conus, Fuchs spot | ||||
53 | OD | 30.37 | − 19.00 | 20/130 | Color vision defect | Tigroid, conus, Fuchs spot | ||
OS | 29.23 | − 14.00 | 20/100 | Tigroid, conus, Fuchs spot | ||||
III-17 | F | 49 | OD | 29.5 | − 21.8 | NA | NA | Tigroid, conus, Fuchs spot |
OS | 29.6 | − 21.8 | NA | Tigroid, conus, Fuchs spot | ||||
55 | OD | 29.54 | − 24.75 | 20/200 | Normal | Tigroid, conus, Fuchs spot | ||
OS | 29.65 | − 23.25 | 20/160 | Tigroid, conus, Fuchs spot | ||||
IV-1 | F | 8 | OD | 24.4 | − 8.4 | 20/20 | Normal | Normal |
OS | 24.1 | − 8.0 | 20/20 | Normal | ||||
14 | OD | 25.22 | − 7.00 | 20/20 | Normal | Normal | ||
OS | 24.90 | − 6.50 | 20/20 | Normal | ||||
IV-5 | F | 11 | OD | NA | − 5.0 | NA | NA | NA |
OS | NA | − 6.0 | NA | NA | ||||
20 | OD | NA | − 7.0 | 20/20 | Normal | NA | ||
OS | NA | − 7.0 | 20/20 | NA | ||||
IV-9 | M | 18 | OD | 23.6 |  + 1.3 | NA | NA | Normal |
OS | 23.7 | 0 | NA | Normal | ||||
31 | OD | 24.1 | − 0.75 | 20/22 | Color vision defect | Normal | ||
OS | 24.03 | − 0.5 | 20/22 | Normal | ||||
IV-10 | M | 34 | OD | 25.01 | − 7.5 | 20/20 | Color vision defect | Conus |
OS | 25.63 | − 11.5 | 20/22 | Conus |
