Table 3 Brain regions showing altered FC with the ITG in the post-taVNS patients compared to the pre-taVNS patients (GRF corrected, voxel p < 0.005, cluster p < 0.05). FC functional connectivity, ITG inferior temporal gyrus, taVNS transcutaneous auricular vagus nerve stimulation, post-taVNS after taVNS treatment, pre-taVNS before taVNS treatment, GRF Gaussian random field, AAL automated anatomical labeling, MNI Montreal Neurological Institute, OFG orbitofrontal gyrus, ANG angular gyrus, IPL inferior parietal lobule, PCG posterior cingulate gyrus, L left, R right.

From: Altered functional brain network patterns in patients with migraine without aura after transcutaneous auricular vagus nerve stimulation

Cluster size

Brain region (AAL name)

MNI coordinates

Peak intensity

x

y

z

79

OFG.R

36

33

− 18

4.85

28

OFG.L

− 39

21

12

4.61

52

ANG.R

51

− 60

27

4.44

99

ANG.L /IPL.L

− 42

− 51

24

4.73

33

PCG.R/L

− 6

− 42

36

3.92