Figure 2

Nodal strength for different epileptogenic states in physiologically relevant frequency bands. Amplitude Envelope Correlation (Top), orthogonalized Amplitude Envelope Correlation (middle), and Phase Locking Value (PLV) (bottom) nodal strength computed for delta, theta, alpha, beta, low- and high-gamma bands on different epileptogenic states. Each epileptogenic state is color-coded: interictal activity with no spikes (“No Spikes”, green-colored), interictal activity with spikes (“Spikes”, blue-colored), pre-ictal activity before the onset of a clinical seizure (“Pre-Ictal”, yellow-colored), ictal activity during a clinical seizure (“Ictal”, red-colored), post-ictal activity after the end of a clinical seizure (“Post-Ictal”, orange-colored). Significant differences are marked with an asterisk (*) (p < 0.05, Wilcoxon’s signed-rank test). P-values are corrected for multiple comparisons using the false discovery rate method. In the box-plot diagrams, the horizontal line indicates the median value, lower and upper edges represent the 25th and 75th percentiles, whiskers extend to the minimum and maximum values (excluding outliers) and points outside the whiskers represent the outliers (i.e., values that are at least 1.5 times the interquartile range below the 25th percentile or above the 75th percentile).