Table 1 Summary of subjects’ characteristics.

From: Intrinsic brain connectivity alterations despite intact pain inhibition in subjects with neuropathic pain after spinal cord injury: a pilot study

Characteristics

SCI-NP (n = 12)

HC (n = 13)

Demographics

 Age (years)

59 (38–66)

53 (37–70)

 Sex (F/M)

1/11

1/12

 Handedness (R/L)

11/1

12/1

 Neurological level of lesion

Th1–L1

–

 AIS (A–D)

6 A, 1 B, 1 C, 4 D

–

 Time since injury (years)

17 (7–39)

–

NP characteristics

 NP intensity (NRS)

4.3 (1.4–6.5)

–

 NP extent (%)

6.8 (1.0–35.5)

–

Questionnaires

 PCS (0–52)

11 (1–20)

11 (0–23)

 BDI (0–63)

3 (0–14)

2 (0–17)

Thermal thresholds (°C)

 WDT

35.8 ± 1.1

36.1 ± 1.2

 HPT

46.1 ± 3.6

43.6 ± 2.8

CPM effect (NRS)

 TS-CPM–TS-Sham

− 0.92 ± 1.08

− 0.41 ± 1.11

CPM profiles (n)

 Inhibitor

10

8

 Non-responder

–

–

 Facilitator

2

5

  1. Information is presented as mean (± standard deviation) or median (range). CPM effect: difference between averaged pain ratings during TS-CPM and TS-Sham. Positive numbers describe a facilitatory CPM effect (facilitator), whilst negative numbers describe an inhibitory CPM effect (inhibitor).
  2. AIS, ASIA Impairment Scale (A, sensorimotor complete; C–D, motor incomplete); BDI, Beck Depression Inventory; CPM, conditioned pain modulation; CS, conditioning stimulus; F, female; HPT, heat pain threshold; L, left; M, male; NRS, numerical rating scale; PCS, Pain Catastrophising Scale; R, right; TS, test stimulus; TS-CPM, test stimulus under CPM; TS-Sham, test stimulus under Sham; WDT, warm detection threshold.
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