Figure 6 | Scientific Reports

Figure 6

From: MicroRNA-146a negatively regulates inflammation via the IRAK1/TRAF6/NF-κB signaling pathway in dry eye

Figure 6

Inflammatory factors IL-6 and IL-8 are negatively regulated by miR-146a during HCEC inflammation. MiR-146a was overexpressed or inhibited in HCECs by transfection with miR-146a mimic or miR-146a inhibitor in the presence of TNF-α. The secretion of the IL-6 and IL-8 proteins in cell culture supernatant was measured by ELISA. The results are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.

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