Table 2 Histological and molecular subtype characteristics of invasive and in situ breast cancer cases (n = 65).

From: Plasma microRNA ratios associated with breast cancer detection in a nested case–control study from a mammography screening cohort

Invasive (n = 57)

In situ (n = 8)

 

n

(%)

 

n

(%)

Histotype

Histotype

 Ductal NOS

30

56.0

Ductal NOS

3

37.5

 Lobular

8

18.0

Solid

1

12.5

 Tubular

4

8.0

Micropapillary

1

12.5

 Other

9

18.0

Papillary

1

12.5

 Missing

6

 

Other

2

25.0

Grade

Grade

 I

18

34.7

I

2

25.0

 II

25

51.0

II

2

25.0

 III

6

14.3

III

4

50.0

 Missing

8

 

Tumour size [I27], mm

pT

1–10

4

50.0

 1a-1b-1mic

25

48.1

11–20

2

25.0

 1c

24

42.6

21 + 

2

25.0

 2 + 

5

9.3

   

 Missing

3

    

Tumour size, mm

   

 1–10

25

46.3

   

 11–20

24

44.4

   

 21 + 

5

9.3

   

 Misssing

3

    

Stage

   

 IA

42

87.5

   

 IIA

3

6.3

   

 IIIC

2

4.2

   

 IV

1

2.1

   

 Missing

9

    

Molecular subtypes

   

ER

   

 Negative

8

15.1

   

 Positive (> 10%)

45

84.9

   

 Missing or undetermined

4

    

PgR

   

 Negative

17

32.1

   

 Positive (> 10%)

36

69.9

   

 Missing or undetermined

4

    

Her2

   

 Negative

45

86.5

   

 Positive

7

13.5

   

 Missing or undetermined

5

    

Ki-67

   

 Negative

39

76.5

   

 Positive (> 20%)

12

23.5

   

 Missing or undetermined

6

    

Intrinsic subtype

   

 Luminal A-like

27

52.9

   

 Luminal B-like (HER2 negative)

13

25.5

   

 Luminal B-like (HER2 positive)

5

9.8

   

 HER2 positive (non luminal)

2

3.9

   

 Triple negative

4

7.8

   

 Missing

6

    
  1. NOS not otherwise specified, pT pathologic evaluation of tumour size, ER estrogen receptor, PgR progesterone receptor, Her2 human epidermal growth factor receptor 2.