Table 4 Results from standard univariable logistic regression and AUCs on RT-qPCR data.

From: Plasma microRNA ratios associated with breast cancer detection in a nested case–control study from a mammography screening cohort

miR ratio

Expression in cases

Expression in controls

OR

(95% CI)

P

AUC

Median

[IQ range]

Median

[IQ range]

miR-26b_miR-142-5p

5.84

[5.08–6.08]

6.05

[5.61–6.44]

0.48

(0.28–0.77)

0.005

0.65

let-7a_miR-22-3p

5.48

[3.54–7.81]

6.94

[4.08–9.89]

0.85

(0.73–0.98)

0.026

0.63

miR-199a-3p_let-7a-5p

1.66

[1.08–2.21]

1.24

[0.92–1.90]

1.64

(1.05–2.63)

0.033

0.61

miR-93-5p_miR-19b-3p

 − 3.07

[− 3.45 to − 2.79]

 − 3.29

[− 3.52 to − 3.04]

2.05

(1.00–4.50)

0.059

0.61

miR-199a-3p_let-7f.-5p

3.65

[2.97–4.15]

3.20

[2.74–3.93]

1.41

(0.97–2.08)

0.077

0.58

miR-15a-5p_miR-16-5p

 − 19.10

[− 20.43 to − 16.51]

 − 17.41

[− 18.50 to − 16.96]

0.82

(0.65–1.02)

0.087

0.63

miR-22-3p_miR-19b-3p

 − 11.04

[− 13.85 to − 9.74]

 − 12.53

[− 15.49 to − 10.03]

1.12

(0.98–1.30)

0.113

0.60

let-7b-5p_miR-19b-3p

 − 3.19

[− 3.61 to − 2.69]

 − 2.83

[− 3.38 to − 2.54]

0.74

(0.47–1.13)

0.176

0.59

let-7f.-5p_miR-146a-5p

 − 7.82

[− 8.60 to − 7.42]

 − 7.57

[− 8.41 to − 6.71]

0.83

(0.62–1.10)

0.210

0.59

miR-27a-3p_miR-122-5p

0.78

[− 0.75–2.06]

0.65

[− 0.80–1.48]

1.12

(0.93–1.36)

0.241

0.54

let-7a-5p_miR-106b-5p

 − 0.17

[− 0.68–0.38]

0.07

[− 0.36–0.70]

0.78

(0.50–1.20)

0.270

0.59

miR-15b-5p_miR-16-5p

 − 10.13

[− 10.92 to − 8.80]

 − 10.12

[− 10.88 to − 9.32]

1.12

(0.92–1.38)

0.276

0.52

miR-335-5p_let-7f.-5p

1.44

[0.78–2.27]

1.03

[0.46–2.03]

1.18

(0.86–1.64)

0.319

0.58

miR-20a-5p_miR-19b-3p

 − 0.50

[− 0.69 to − 0.14]

 − 0.48

[− 0.76 to − 0.21]

0.78

(0.45–1.28)

0.351

0.48

let-7f.-5p_miR-19b-3p

 − 7.79

[− 8.36 to − 7.08]

 − 7.49

[− 8.16 to − 6.66]

0.87

(0.64–1.16)

0.355

0.57

let-7f.-5p_miR-103a-3p

 − 1.23

[− 1.88 to − 0.79]

 − 1.19

[− 1.66 to − 0.82]

0.86

(0.61–1.20)

0.390

0.53

let-7a-5p_miR-320a

 − 4.30

[− 4.94 to − 3.49]

 − 4.08

[− 4.63 to − 3.16]

0.88

(0.65–1.17)

0.399

0.57

miR-30d-5p_miR-20a-5p

 − 4.27

[− 4.79 to − 4.04]

 − 4.29

[− 4.62 to − 4.03]

0.97

(0.63–1.50)

0.905

0.50

miR-21-5p_miR-23a-5p

4.34

[3.93–4.91]

4.30

[3.80–4.95]

1.02

(0.66–1.58)

0.917

0.52

miR-101-3p_miR-19b-3p

 − 8.09

[− 8.63 to − 7.65]

 − 8.17

[− 8.64 to − 7.69]

0.99

(0.70–1.41)

0.969

0.49

  1. OR odds ratio, CI confidence interval, AUC area under the ROC curve.
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