Figure 3
From: Computational modeling and minimization of unintended neuronal excitation in a LIFU stimulation
The beam patterns and neuronal spike patterns of transcranial stimulation with single transducer array, demonstrating the minimized OTAA of CORB compared with two benchmarks. The distance between the target point and array is approximately 7.33 cm. (a–c): Approximate beam patterns for continuous-wave stimulation generated by the conjugate benchmark, the off-target suppression benchmark, and CORB, respectively. The color maps demonstrate the spatial distribution of mean ultrasound intensity normalized by the target signal intensity (0.078 W/cm\(^{2}\))22. (d–f): Neuronal spike count map of conjugate benchmark, the off-target suppression benchmark, and CORB, respectively, in a continuous-wave LIFU stimulation (target intensity: 0.078 W/cm\(^{2}\); duration: 100 ms). Ultrasound pressures at all other points are scaled proportionally to the target based on the mean intensity distributions in (a)–(c). (g): The OTAA in log-scale with different stimulation intensities (duration: 100 ms). (textbfh) The OTAA in log-scale with different stimulation durations (target intensity: 0.078 W/cm\(^{2}\)).
