Figure 2

Estimated percentile charts with confidence intervals. Sex-specific percentile charts for alkaline phosphatase, hemoglobin, and creatinine, showing the 2.5th and 97.5th percentile (usually referred to as reference intervals) (dotted-dashed red lines), the 10th and 90th percentile (dotted yellow lines), the 25th and 75th percentile (dashed green lines) and the 50th percentile (solid blue line). The color-shaded area around the curves show the estimated 95% confidence interval potentially extended to include the estimates of the original model. The scale of the x-axis is threefold, showing the first 30 days of life, months from 1 to 12 and years from 1 to 18 to account for the dynamics in neonates and infants. For results shown on linear age scale, see Supplemental Fig. S2.