Figure 3 | Scientific Reports

Figure 3

From: A pipeline for the fully automated estimation of continuous reference intervals using real-world data

Figure 3

Comparison of estimated reference intervals to previously established discrete and continuous reference intervals. Each plot shows the estimated continuous reference intervals (RIs) (2.5th and 97.5th percentiles) with confidence intervals (CIs) (green solid lines and green shaded area) in comparison to the RIs (with CIs) established as part of the CALIPER study (dotted orange lines and orange colored region for results using quantile regression (QuantReg); dotted black lines for results using LMS method), the RIs determined within the PEDREF project (dashed purple lines) and the discrete RIs (with CIs) stated in the manufacturers’ package inserts (dashed-dotted blue lines and blue colored region).

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