Figure 1

Identification of ICD-associated subtypes by consensus clustering. (A) Heatmap shows 34 ICD gene expression profiles among normal and LUAD samples in TCGA database. (B) Protein–protein interactions among the ICD-associated genes (C) Heatmap depicts consensus clustering solution (k = 2) for 34 genes in 539 LUAD samples (D,E) Delta area curve of consensus clustering indicates the relative change in area under the cumulative distribution function (CDF) curve for k = 2 to 9. (F) Tracking Plot of consensus clustering indicates the relative change of class that samples belongs to for k = 2 to 9. (G) Heatmap of 34 ICD-related gene expressions in different subtypes. Red represents high expression and blue represents low expression.