Table 3 Baseline and serial postinfarct HRV and HRC metrics.

From: Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction

 

HRV and HRC metrics

Control

Inferior STEMI

Acute stage (N = 33)

3 months (N = 20)

6 months (N = 22)

1 year (N = 31)

Mean NN (ms)

793.6 (711.7–903.5)

823.6 (691.5–882.9)

725.1 (672.3–801.1)

753.1 (716.7–827.5)

720.9 (689.1–820.1)

 P value*

–

0.338

0.009

0.124

0.046

 P value#

–

–

0.041

0.585

0.366

SDNN (ms)

73.5 (58.2–89.2)

44.2 (27.9–50.3)

36.8 (29.8–44.8)

35.2 (30.4–40.8)

36.0 (24.9–46.0)

 P value*

–

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 P value#

–

–

0.601

0.636

0.518

pNN20 (%)

21.1 (12.1–39.0)

24.0 (16.4–38.8)

23.8 (14.6–32.7)

21.3 (14.8–31.0)

18.4 (12.0–32.2)

 P value*

 

0.822

0.895

0.470

0.680

 P value#

–

–

0.356

0.167

0.331

pNN50 (%)

2.4 (0.8–8.0)

2.1 (0.7–7.5)

2.9 (1.0–4.7)

1.6 (0.9–2.9)

1.7 (0.7–3.8)

 P value*

–

0.425

0.143

0.080

0.247

 P value#

–

–

0.170

0.086

0.446

LF (ms2)

39.2 (16.8–65.6)

198.2 (71.8–347.3)

149.3 (54.1–213.8)

119.1 (57.1–213.2)

126.7 (60.5–178.8)

 P value*

–

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 P value#

–

–

0.231

0.219

0.124

HF (ms2)

14.6 (5.1–28.4)

56.3 (20.6–131.0)

27.9 (19.4–54.8)

25.6 (18.8–45.8)

23.7 (15.8–51.0)

 P value*

–

0.005

0.102

0.135

0.024

 P value#

–

–

0.087

0.097

0.156

LF/HF

2.8 (1.2–4.7)

3.9 (2.4–5.7)

4.1 (3.3–6.7)

5.1 (2.8–7.1)

4.7 (3.0–7.0)

 P value*

–

0.086

0.004

0.002

0.003

 P value#

–

–

0.448

0.354

0.343

DFAα1

1.2 (0.9–1.3)

1.2 (1.0–1.3)

1.2 (1.0–1.3)

1.2 (1.0–1.4)

1.2 (1.1–1.3)

 P value*

–

0.929

0.310

0.159

0.325

 P value#

–

–

0.327

0.090

0.182

DFAα2

1.1 (1.1–1.2)

1.0 (1.0–1.1)

1.1 (1.0–1.2)

1.1 (1.1–1.1)

1.1 (1.1–1.2)

 P value*

–

 < 0.001

0.244

0.350

0.307

 P value#

–

–

 < 0.001

 < 0.001

 < 0.001

MSE slope 1–5

0.044 (– 0.018–0.081)

0.042 (− 0.009–0.074)

0.048 (-0.020–0.083)

0.054 (-0.008–0.087)

0.031 (0.009–0.079)

 P value*

–

0.944

0.677

0.503

0.561

 P value#

–

–

0.809

0.421

0.497

Scale5

1.2 (1.1–1.4)

1.5 (1.2–1.6)

1.3 (1.0–1.5)

1.3 (1.1–1.4)

1.2 (1.0–1.5)

 P value*

–

0.032

0.766

0.905

0.601

 P value#

–

–

0.022

0.021

0.004

Area 1–5

6.0 (5.1–6.6)

5.2 (4.4–5.9)

4.6 (3.6–5.3)

4.7 (4.2–5.4)

4.4 (3.8–5.3)

 P value*

–

0.003

 < 0.001

 < 0.001

 < 0.001

 P value#

–

–

0.006

0.014

 < 0.001

Area 6–20

20.5 (18.7–22.6)

22.4 (17.6–24.1)

20.7 (16.5–22.3)

21.2 (18.8–22.6)

19.6 (17.9–22.9)

 P value*

–

0.429

0.186

0.441

0.168

 P value#

–

–

0.036

0.098

0.010

  1. *Using student T test compared with control subjects.
  2. #Using paired T test, compared with inferior STEMI acute stage data.
  3. SDRR standard deviation of normal heartbeats, pNN20 percentage of the successive change in RR interval exceeds 20 ms, pNN50 percentage of the successive change in RR interval exceeds 50 ms, LF low frequency, HF high frequency, DFA detrended fluctuation analysis, MSE multiscale entropy, slope 1–5 slope between scale 1–5, Area 1–5 the area under scale 1–5, Area 6–20 the area under scale 6–20.
  4. Significant values are in bold.
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