Figure 3
LASSO and multivariate regression models screening genes. (A) LASSO coefficient profiles of genes in STAD; dotted vertical lines were drawn at the optimal values by using the minimum criteria. (B) LASSO coefficient profiles of the candidate OS-related GRGs with nonzero coefficients determined by the optimal lambda. A coefficient profile plot was produced against the logλ sequence. (C) Forest plot of several genes was involved in the ceRNA network. (D) Risk score analyses of GC patients in the training cohort based on the seven-GRGs signature. Distribution of risk scores per patient. (E) Relationships between survival status and survival times of GC patients ranked by risk score. The black dotted line represents the optimum cut-off point dividing patients into low and high-risk groups.
