Figure 1 | Scientific Reports

Figure 1

From: Knockdown of Secernin 1 inhibit cell invasion and migration by activating the TGF-β/Smad3 pathway in oral squamous cell carcinomas

Figure 1

SCRN1 expression is significantly increased in OSCC tissues and cell lines. (A) Normal tissue was negative for SCRN1 staining (× 500). (B) Weak expression of SCRN1 was defined as low expression in OSCC (× 500). (C) Strong expression of SCRN1 with cytoplasmic and membranous staining was defined as high expression in OSCC (× 500). (D, E) The expression levels of SCRN1 were measured in 15 paired OSCC tissues and adjacent normal mucosa by WB. The data are presented as the mean ± SD. ***p < 0.001. (F, G) The expression levels of SCRN1 in the HSC3, HSC6, SCC15, SCC25, UM1 and UM2 cell lines were examined by WB. Significant differences were determined using t test. The data are presented as the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 and ***p < 0.001.

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