Table 1 Demographic and clinical characteristics of influenza-infected children before, during and at the end of treatment.
Characteristic | Control group (N = 48) | Navax group (N = 44) | p value | ||||||
|---|---|---|---|---|---|---|---|---|---|
Before treatment | After treatment | Before treatment | After treatment | Before treatment | After treatment | ||||
Day 0 | Day 2 | Day 5 | Day 0 | Day 2 | Day 5 | Day 0 | Day 2 | Day 5 | |
Age (months) | |||||||||
  ≥ 4–12, n (%) | 9 (18.75) |  |  | 7 (15.91) |  |  | 0.72 |  |  |
  > 12–84, n (%) | 39 (81.25) |  |  | 37 (84.09) |  |  |  |  | |
Gender | |||||||||
 Male, n (%) | 25 (52.08) |  |  | 24 (54.55) |  |  | 0.81 |  |  |
 Female, n (%) | 23 (47.92) |  |  | 20 (45.45) |  |  |  |  | |
 Days of sickness before treatment | 3.1 |  |  | 2.9 |  |  | 0.57 |  |  |
Typical symptoms due to influenza infection n (%) | |||||||||
 Runny nose, n (%) | 48 (100) | 48 (100) | 12 (25.00) | 44 (100) | 30 (68.18) | 0 (0.00) | 0.97 | 0.01 | 0.02 |
 Dry rales, n (%) | 33 (68.75) | 32 (66.67) | 10 (20.83) | 22 (50.00) | 18 (40.91) | 0 (0.00) | 0.07 | 0.01 | 0.03 |
 Moist rales n (%) | 21 (43.75) | 21 (43.75) | 6 (12.50) | 13 (39.55) | 12 (27.27) | 0 (0.00) | 0.16 | 0.10 | 0.08 |
Temperature (℃) | |||||||||
 Normal (≤ 37.5), n (%) | 4 (8.33) | 13 (27.08) | 48 (100) | 3 (6.82) | 31 (70.45) | 44 (100) | 0.78 | 0.0001 | 0.97 |
 Fever (> 37.5), n (%) | 44 (91.67) | 35 (72.92) | 0 (0.00) | 41 (93.18) | 13 (29.55) | 0 (0.00) | |||
SpO2 (%) | |||||||||
  ≥ 95%, n (%) | 48(100) | 48(100) | 48(100) | 44 (100) | 44 (100) | 44 (100) | 0.97 | 0.97 | 0.97 |
  < 95%, n (%) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | |||
Pulse (beats/min) | |||||||||
  ≥ 4–12 months (> 140), n (%) | 3 (6.82) | 3 (6.25) | 0 (0.00) | 3 (6.82) | 2 (4.55) | 0 (0.00) | 0.91 | 0.72 | –a |
  > 12 months (> 120), n (%) | 28 (58.33) | 26 (54.17) | 0 (0.00) | 25 (56.82) | 16 (36.36) | 0 (0.00) | 0.88 | 0.09 | –a |
Breath (beats/min) | |||||||||
  ≥ 4–12 months (> 40), n (%) | 2 (4.17) | 1 (2.08) | 0 (0.00) | 1 (2.27) | 0 (0.00) | 0 (0.00) | 0.61 | 0.53 | –a |
  > 12 months (> 32), n (%) | 20 (41.67) | 11 (22.92) | 0 (0.00) | 12 (27.27) | 6 (13.64) | 0 (0.00) | 0.15 | 0.26 | –a |
