Figure 1

Protective effects of mild hypothermia on hippocampus neurological damage and cognitive dysfunction after cerebral ischemia-perfusion injury. (a) HE staining; (b) Nissl staining; the time (c) and path length (d) that rats spent to find the platform during 4 training days; The time (e) and distance (f) that rats spent in the target quadrant in the probe test; (g) the routes of rats in the probe test. Sham: Sham-operation group; IR: cerebral IR injury followed by normothermia (37 °C) group; IR + MH: cerebral IR injury followed by 4 h of MH (32 °C) group. Scale bars = 50 µm. Results are presented as the mean ± standard deviation (SD). *P < 0.05.