Figure 2
From: Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction
Fibulin-3 is elevated in left ventricular tissue and plasma of heart failure patients. (a,b) Fibulin-3 was significantly elevated vs controls in the ventricular tissue (LC–MS/MS analysis) and plasma of heart failure (HF) patients. (c) Circulating fibulin-3 in HF patients was significantly positively correlated with established biomarkers N-terminal pro b-type natriuretic peptide (NT-proBNP), high sensitivity C-reactive protein (hs-CRP), and significantly negatively correlated with LV ejection fraction (LVEF). Ventricular tissue, HF n = 15, control n = 10; Plasma n ≥ 55 including non-failing and HF patient plasma.
