Table 1 Characteristics of patients in training cohort and validation cohort.

From: A novel nomogram predicting overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in portal hypertension patients

Characteristics

Training (n = 207)

Validation (n = 89)

p value

OHE

 No

168 (81.16)

69 (77.53)

0.5262

 Yes

39 (18.84)

20 (22.47)

 

Age, years

51.46 ± 12.88

52.89 ± 12.64

0.2580

Gender

 Female

62 (29.96)

31 (34.8)

0.4156

 Male

145 (70.04)

58 (65.2)

 

TIPS indication

 Variceal bleeding

123 (59.4)

65 (73)

0.0900

 Ascites

49 (23.7)

11 (12.4)

 

 Bleeding combine with ascites

20 (9.7)

9 (10.1)

 

 Other

15 (7.2)

4 (4.5)

 

Causes of cirrhotic

 Virus

127 (61.35)

52(58.4)

0.9025

 Alcoholic

24 (11.59)

10 (11.2)

 

 Biliary

6 (2.89)

2 (2.2)

 

 Other

50 (24.15)

25 (28.1)

 

Stent size, mm

 7

42 (20.3)

22 (24.7)

0.3648

 8

144 (69.6)

62 (69.7)

 

 10

21 (10.1)

5 (5.6)

 

Puncture site of portal vein

 Left branch

122 (58.9)

67 (75.3)

0.0087

 Right branch

52 (25.1)

9 (10.1)

 

 Bifurcation

33 (15.9)

13 (14.6)

 

Child–Pugh grade

 A Class

79 (38.2)

40 (44.9)

0.5512

 B Class

110 (53.1)

42 (47.2)

 

 C Class

18 (8.7)

7 (7.9)

 

MELD score

6.42 (3.78–10.16)

6.78 (4.22–9.70)

0.9386

ICG-R15

26.3 (18–45)

33.6 (21.15–52.8)

0.0432

PPG decline in value, mmHg

11 (8–14)

10 (7–14)

0.5631

Percentage decline in PPG

45.45 (40–52.38)

44.44 (33.33–52.28)

0.1823

ALT, U/L

21 (14–32)

19 (13–27)

0.1927

AST, U/L

28 (20–42)

27 (23–37)

0.5304

Albumin, g/L

34.72 ± 5.31

34.99 ± 4.75

0.6552

Total bilirubin, μmol/L

23.7 (16.9–35.6)

23.9 (16.5–32)

0.3466

Creatinine, μmol/L

60 (51–74)

62 (52–72.5)

0.7552

PT, s

14.5 (13.1–16.2)

14.4 (13.2–16.25)

0.8248

INR

1.31 (1.20–1.45)

1.33 (1.21–1.48)

0.4073

BUN, mmol/L

5.53 (4.20–7.71)

5.17 (4.10–7.28)

0.2996

Na, mmol/L

139 (136–142)

140 (136–141)

 < 0.001

Blood ammonia, umol/L

45.5 (36.1–58.9)

36.6 (31–48.35)

0.460

  1. OHE overt hepatic encephalopathy, TIPS transjugular intrahepatic portosystemic shunt, ALT alanine transaminase, AST aspartate transaminase, PT prothrombin time, MELD Model For End-Stage Liver Disease, ICG-R15 indocyanine green retention rate at 15 min, PPG Portal pressure gradient, INR international normalized ratio.