Figure 4
From: Reconditioned monocytes are immunomodulatory and regulate inflammatory environment in sepsis
RM transplantation in the mouse model of sepsis. (A) Survival rates of mice with CLP-induced sepsis following RM treatment shown as Kaplan–Meier survival curve. (B) Temperature changes in mice with CLP-induced sepsis following RM treatment. Surface body temperatures were measured at different time points in the Sham group, CLP group, and different treatment groups. Treatment with RM 4 h post-surgery attenuated temperature decline at 6 h and 18 h post-CLP (n = 3). (C) Bar graphs depicting mean concentrations of cytokines in serum of CLP mice and different treatment groups. Serum levels of IL6, IL10 and MCP1 were quantified at experiment termination (22 ± 2 h) in different experimental groups (n = 3). Results are presented as mean with SD.
