Table 1 Characteristics of patients (n, %).

From: High endothelial venules predict response to PD-1 inhibitors combined with anti-angiogenesis therapy in NSCLC

Characteristics

Total

Combined with anti-angiogenosis group

Non-combined with anti-angiogenosis group

χ2

P

Total

190

96

94

  

Sex

   

0.566

0.452

 Male

142 (74.7)

74 (77.1)

68 (72.3)

  

Female

48 (25.3)

22 (22.9)

26 (27.7)

  

Age, years

   

0.52

0.471

 ≥ 65

92 (48.4)

44 (45.8)

48 (59.6)

  

 < 65

98 (51.6)

52 (54.2)

46 (40.4)

  

Histology

   

0.965

0.617

 Adenocarcinoma

120 (63.2)

61 (63.5)

59 (62.8)

  

 Squamous cell carcinomas

42 (22.1)

23 (24.0)

19 (20.2)

  

 Other

28 (14.7)

12 (12.5)

16 (17.0)

  

Disease stage at diagnosis

   

0.445

0.505

 III

29 (15.3)

13 (13.5)

16 (17.0)

  

 IV

161 (84.7)

83 (86.5)

78 (83.0)

  

PS score

   

0.73

0.393

 0–1

168 (88.4)

83 (86.5)

85 (90.4)

  

 ≥ 2

22 (11.6)

13 (13.5)

9 (9.6)

  

EGFR mutation status

   

4.394

0.111

 Negative

89 (46.8)

52 (54.2)

37 (39.4)

  

 Positive

41 (21.6)

19 (19.8)

22 (23.4)

  

 Unknown

60 (31.6)

25 (26.0)

35 (37.2)

  

Line of therapy

   

0.317

0.573

 1

65 (34.2)

31 (32.3)

34 (36.3)

  

 ≥ 2

125 (65.8)

65 (67.7)

60 (63.8)

  

PD-L1 TPS

   

1.23

0.746

 ≥ 50%

30 (15.8)

13 (13.5)

17 (18.1)

  

 1–49%

18 (9.5)

10 (10.4)

8 (8.5)

  

 < 1%

20 (10.5)

9 (9.4)

11 (11.7)

  

 Unknown

122 (64.2)

64 (66.7)

58 (61.7)

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