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Figure 1

From: Analytical sensitivity of a method is critical in detection of low-level BRCA1 constitutional epimutation

Figure 1

Examples of the MS-HRM results for the BRCA1 constitutional methylation positive and negative samples: (A) sample positive for methylation run at 59 °C; (B) sample positive for methylation but not reproducibly detectable run at 61 °C; (C) sample negative for methylation run at 59℃. Color legend: red—100% methylated control, green—0% non-methylated control, blue—1% calibration control, orange—test sample.

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