Table 6 Differences in demographics and clinical parameters of dry eye disease (DED) between subjects with and without ocular Demodex infestation in subgroup 3.

No. of subjects

67

118

–

Number of Demodex mites

(per 4 eyelashes in a unilateral eye)

0

2.37 \(\pm\) 1.44

–

Demographics

 Age (yrs)^a

69.7 \(\pm\) 6.9

69.2 \(\pm\) 7.0

0.625

 Male/female (% female)^b

20/47 (70.1%)

29/89 (75.4%)

0.435

Clinical parameters

 OSDI (score)^a

39.3 \(\pm\) 21.0

38.8 \(\pm\) 22.2

0.729

 Tear MMP-9 (Gr)^a

2.00 \(\pm\) 1.05

2.18 \(\pm\) 1.10

0.316

 Tear osmolarity (mOsm/L)^a

311.3 \(\pm\) 20.3

302.2 \(\pm\) 22.5

0.242

 Corneal erosions score^a

0.80 \(\pm\) 1.56

0.97 \(\pm\) 1.68

0.274

 SICCA OSS^a

0.57 \(\pm\) 1.26

0.68 \(\pm\) 1.11

0.469

 Tear BUT (s)^a

5.39 \(\pm\) 2.37

5.95 \(\pm\) 2.56

0.290

 Schirmer I without anesthesia (mm)^a

11.15 \(\pm\) 9.25

10.38 \(\pm\) 7.89

0.961

 MG expressibility (Gr)^a

1.65 \(\pm\) 0.64

1.64 \(\pm\) 0.58

0.936

 Meibum quality (Gr)^a

1.86 \(\pm\) 0.77

1.91 \(\pm\) 0.58

0.772