Table 2 Single-nucleotide polymorphism associated with calcineurin inhibitor toxicity in multiple analyses.

From: Association of high intra-patient variability in tacrolimus exposure with calcineurin inhibitor nephrotoxicity in kidney transplantation

rs number

Gene name

Hazard ratio

95% CI

p-value

rs1045642

ABCB1

3.61

0.17–77.32

0.411

rs1128503

ABCB1

0.98

0.27–3.51

0.974

rs15524

CYP3A5

2.11

0.59–7.63

0.254

rs2032582

ABCB1

7.67

0.40–148.55

0.178

rs2276707

NR1I2

0.67

0.16–2.53

0.550

rs28371759

CYP3A4

25.50

2.36–275.18

0.008

rs3740066

ABCC2

3.08

0.82–11.56

0.096

rs776746

CYP3A5

1.67

0.46–6.04

0.437

rs890293

CYP2J2

3.61

0.58–22.62

0.170

  1. SNP single-nucleotide polymorphism, CNI calcineurin inhibitor, CI confidence interval.
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