Figure 3

Immune gene module deconvolution. (A) Heatmap showing the expression of immune module genes in the five cell types. (B) Top GOs enriched in MG genes. All 3 GO terms were based on Biological Processes (BP) (C) Top GOs enriched in OG genes based on BP. (D) Top GOs enriched in VC genes. Hemostatis was based on Reactome Gene Sets, while Blood vessel morphogenesis and Angiogenesis were based on BP. (E) Correlation network of selected module genes from MG, OG and VC. (F) Dot plot showing gene fold changes of old versus young animals from our deconvoluted data, Ximerakis et al.¹², Allen et al.¹³ and Lee et al.¹⁴. MG genes are denoted in pink, OG genes in gold, and VC genes in green.