Figure 5 | Scientific Reports

Figure 5

From: Superior performance of biofilm versus planktonic Limosilactobacillus reuteri in protection of the intestines and brain in a piglet model of necrotizing enterocolitis

Figure 5

Comparison of Lr (planktonic) and Lr-DM-maltose in a piglet model of necrotizing enterocolitis (NEC). In Experiment 2, piglets were randomized to NEC + Saline (N = 15), NEC + Lr (planktonic) (N = 16), NEC + Lr-DM-maltose (N = 15) groups. The following data represent the combined results of 3 independent experiments. (a) Clinical Sickness Scores (CSS), *p < 0.05, (b) gross injury scores, (c) histologic injury scores, (d) severe histologic injury, (e) bacterial translocation, (f) Definitive NEC (D-NEC) score, and (g) percent death associated with D-NEC. Statistical significance was calculated using 2-way analysis of variance (ANOVA) for CSS. Columns indicate group means and error bars show standard error of the mean (SEM). The Kruskal–Wallis test was performed for gross injury scores, histologic injury scores, severe histologic injury, bacterial translocation, and D-NEC score. Percent death associated with D-NEC was analyzed using the log-rank (Mantel-Cox) test with Bonferroni correction.

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