Figure 4

Receiver operating characteristic (ROC) curve analysis of serum and exosomal miR-1258 and other biomarkers to diagnose AECOPD. (A) Discriminate AECOPD from normal controls; (B) discriminate AECOPD from SCOPD; (C) the combined detection of exosomal miR-1258 and NLR to discriminate AECOPD from normal controls; (D) the combined detection of exosomal miR-1258 and NLR to discriminate AECOPD from SCOPD. Abbreviation: AUC: area under the curve; NLR: neutrophil to lymphocyte ratio; CRP: C-reactive protein; WBC; white blood cell count; NEU: neutrophil count.