Table 3 Pre-experienment for choosing biomarker to diagnose SCOPD from AECOPD.

From: Serum exosomal microRNA-1258 may as a novel biomarker for the diagnosis of acute exacerbations of chronic obstructive pulmonary disease

 

Serum

Exosome

AECOPD(n = 19)

SCOPD(n = 18)

p value

AECOPD(n = 19)

SCOPD(n = 18)

p value

miR-1258

0.161 ± 0.108

0.087 ± 0.069

0.018

0.380 ± 0.225

0.204 ± 0.126

0.006

miR-182-3p

0.041 ± 0.012

0.046 ± 0.023

0.387

0.047 ± 0.005

0.041 ± 0.007

0.037

miR-660-5p

0.291 ± 0.044

0.309 ± 0.115

0.546

0.367 ± 0.070

0.327 ± 0.058

0.062

miR-148-3p

0.349 ± 0.271

0.381 ± 0.200

0.682

0.645 ± 0.077

0.612 ± 0.064

0.262

miR-27a-5p

0.298 ± 0.078

0.316 ± 0.055

0.409

1.091 ± 0.247

1.135 ± 0.177

0.621

miR-497-5p

0.696 ± 0.610

1.698 ± 0.482

0.988

6.089 ± 1.120

6.742 ± 1.160

0.181