Figure 4 | Scientific Reports

Figure 4

From: Serum 25-hydroxyvitamin D level is associated with short-term glycemic variability metrics derived from continuous glucose monitoring in T2DM

Figure 4

Multivariable-adjusted associations of measures of 25OHD with HbA1c and glycemic variability metrics. (A) Associations of measures of 25OHD with HbA1c. Model 1 was adjusted for sex, age, BMI, DM duration, SBP, and DBP; Model 2 was adjusted for model 1 + TC, TG, eGFR, cardiovascular and cerebrovascular disease, antidiabetic agents, antihypertension agents and lipid-lowering agents; Model 3 was adjusted for model 2 + SD; Model 4 was adjusted for model 2 + CV; Model 5 was adjusted for model 2 + MAGE; and Model 6 was adjusted for model 2 + TIR. (B) Associations of measures of 25OHD with glycemic variability metrics. Model 1 was adjusted for sex, age, BMI, DM duration, SBP, DBP, and HbA1c; Model 2 was adjusted for model 1 + TC, TGs, eGFR, cardiovascular and cerebrovascular disease, antidiabetic agents, antihypertension agents and lipid-lowering agents. Point estimates (unstandardized β [β]) and 95% CIs represent the difference (in SD) in HbA1c or glycemic variability metrics per SD increase in the measure of 25OHD.

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