Figure 2
From: Circ_ZNF778_006 promoted ESCC progression by upregulating HIF-1α expression via sponging miR-18b-5p
the expression of circ_ZNF778_006 in ESCC cells treated with 5-Fu or Cisplatin. (A) RT-PCR assay was applied to detect the expression of circ_ZNF778_006 and ZNF778 mRNA treated with different sh-RNA in the EC9706 cell line. **p < 0.05 vs sh-NC, ***p < 0.01 vs. sh-NC. (B) The expression of circ_ZNF778_006 and ZNF778 mRNA transfected with oe-cZNF778_006 in TE-1 cell line. ***p < 0.01 versus. blank vector. (C) The survival rate of EC9706 cells transfected with sh-circ_ZNF778-006 was lower than that with sh-NC treated with same levels of 5-Fu, respectively. ***p < 0.01. (D) The survival rate of TE-1 cells transfected with circ_ZNF778-006 was higher than that with sh-NC treated with same levels of 5-Fu, respectively. ***p < 0.01. (E) The survival rate of EC9706 cells transfected with sh-circ_ZNF778-006 was lower than that with sh-NC treated with same levels of Cisplatin, respectively. ***p < 0.01. (F) The survival rate of TE-1 cells transfected with circ_ZNF778-006 was higher than that with empty vector treated with same levels of Cisplatin, respectively. ***p < 0.01.
