Figure 3
From: Circ_ZNF778_006 promoted ESCC progression by upregulating HIF-1α expression via sponging miR-18b-5p
circ_ZNF778_006 deficiency suppressed proliferation, migration, invasion of ESCC cells. (A) The proliferation of EC9706 cells treated with sh-RNA was lower than that with sh-NC as the increasing time. **p < 0.05 vs sh-NC, ***p < 0.01 vs. sh-NC. (B) The proliferation of TE-1 cells treated with oe-cZNF778_006 was higher than that with empty vector as the increasing time. **p < 0.05 vs blank vector, ***p < 0.01 vs. blank vector. (C) The invasion and migration of EC9706 cells treated with sh-RNA was lower than that with sh-NC. ***p < 0.01 vs. sh-NC. (D) The invasion and migration of TE-1 cells treated with oe-cZNF778_006 was higher than that with empty vector. ***p < 0.01 vs. blank vector. (E) The expression of Ki-67, N-cadherin, and Vimentin mRNA in EC9706 cells treated with sh-RNA was highest in four groups, respectively. But the expression of E-cadherin was lowest. (F) The expression of Ki-67, E-cadherin, N-cadherin, and Vimentin mRNA in TE-1 cells treated with oe-circ_ZNF778_006 was highest in four groups, respectively. But the expression of E-cadherin was lowest.
