Figure 7
From: Circ_ZNF778_006 promoted ESCC progression by upregulating HIF-1α expression via sponging miR-18b-5p
circ_ZNF778_006 can promoted ESCC cell proliferation in vivo. (A) The volume of xenograft tumor in nude mice. (B) The expression of HIF-1a was highest in xenograft tumor of nude mice treated with oe-circRNA778_006 was largest. ***p < 0.01. (C) The subcutaneous tumor volume in the xenograft tumor of nude mice treated with sh-circRNA778_006 was lower than that with sh-NC. *p < 0.05, **p < 0.01. (D) The tumor weight in the xenograft tumor of nude mice treated with sh-circRNA778_006 was lower than that with sh-NC. **p < 0.01. (E) The subcutaneous tumor volume in the xenograft tumor of nude mice treated with oe-circRNA778_006 was higher than that with sh-NC. *p < 0.05, **p < 0.01. (F) The tumor weight in the xenograft tumor of nude mice treated with oe-circRNA778_006 was higher than that with sh-NC. **p < 0.01. (G) The expression of Ki-67, N-cadherin, and Vimentin mRNA in rats treated with oe-circRNA was highest in four groups, respectively. But the expression of E-cadherin was lowest.
