Figure 1 | Scientific Reports

Figure 1

From: Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2

Figure 1

Study cohort and serological response against the Wuhan-Hu-1 strain. (A) Demographic distribution of cohort. (B) Detailed information on study cohort according to age, gender, ethnicity, and comorbidities (C) Quantification of serological IgG antibodies at four timetpoints against SARS-CoV-2 NP, spike and RBD. (D) Neutralizing response at four timepoints assessed by PVNT. Multiple linear regression was employed to evaluate the response at each timepoint. The model contained all parameters described in this study. Results were statistically significant for (E) age groups and (F) sex. All results were analyzed by Kruskal–Wallis test followed by Dunn’s test, N = 168, data represented as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Back to article page