Table 4 Relationship between the asymmetry index of thalamic subnuclei volume and neurocognitive scores in patients with (a) left-TLE and (b) right-TLE; correlation coefficient (p value).

From: Morphological and metabolic asymmetries of the thalamic subregions in temporal lobe epilepsy predict cognitive functions

(a) Asymmetry index

Anterior

Lateral

Ventral

Intralaminar

Medial

Posterior

Whole thalamus

FSIQ

0.408 (0.059)

0.277 (0.211)

 − 0.043 (0.849)

 − 0.015 (0.948)

 − 0.054 (0.812)

 − 0.055 (0.808)

 − 0.040 (0.859)

VIQ

0.636 (0.001**)

0.357 (0.103)

0.285 (0.199)

0.255 (0.253)

0.168 (0.455)

0.067 (0.766)

0.214 (0.339)

PIQ

0.305 (0.168)

0.196 (0.381)

 − 0.195 (0.385)

 − 0.095 (0.675)

 − 0.099 (0.662)

 − 0.099 (0.660)

 − 0.136 (0.546)

WMI

0.412 (0.057)

0.242 (0.278)

0.043 (0.850)

0.074 (0.745)

0.143 (0.526)

0.078 (0.729)

0.086 (0.704)

PSI

 − 0.015 (0.948)

0.216 (0.335)

 − 0.053 (0.815)

 − 0.085 (0.705)

 − 0.442 (0.040)

 − 0.234 (0.295)

 − 0.159 (0.480)

Onset age

0.274 (0.194)

0.322 (0.125)

0.253 (0.233)

0.318 (0.129)

0.104 (0.627)

0.269 (0.204)

0.321 (0.126)

Disease duration

 − 0.392 (0.058)

 − 0.387 (0.062)

 − 0.458 (0.024*)

 − 0.467 (0.021*)

 − 0.488 (0.016*)

 − 0.432 (0.035*)

− 0.525 (0.008**)

(b) Asymmetry index

Anterior

Lateral

Ventral

Intralaminar

Medial

Posterior

Whole thalamus

FSIQ

0.413 (0.142)

0.226 (0.437)

0.267 (0.356)

0.072 (0.808)

0.278 (0.336)

0.450 (0.106)

0.557 (0.039*)

VIQ

0.455 (0.102)

0.359 (0.208)

0.015 (0.960)

0.026 (0.929)

0.178 (0.542)

0.358 (0.209)

0.326 (0.255)

PIQ

0.447 (0.109)

0.328 (0.252)

0.197 (0.499)

0.156 (0.594)

0.275 (0.342)

0.476 (0.086)

0.538 (0.047*)

WMI

0.251 (0.387)

0.162 (0.581)

0.291 (0.313)

0.148 (0.614)

0.200 (0.493)

0.574 (0.032*)

0.615 (0.019*)

PSI

0.695 (0.006**)

0.431 (0.124)

0.109 (0.711)

 − 0.037 (0.900)

0.146 (0.619)

 − 0.046 (0.877)

0.210 (0.470)

Onset age

0.289 (0.295)

0.311 (0.259)

 − 0.186 (0.507)

 − 0.279 (0.314)

0.136 (0.630)

0.236 (0.397)

0.314 (0.254)

Disease duration

 − 0.005 (0.985)

 − 0.328 (0.233)

0.450 (0.093)

 − 0.088 (0.756)

 − 0.306 (0.267)

 − 0.341(0.214)

 − 0.203 (0.469)

  1. FSIQ Full-Scale IQ; VIQ Verbal IQ; PIQ Performance IQ; WMI Working Memory Index; PSI Processing Speed Index.
  2. *p < 0.05; **p < 0.01.
  3. Spearman partial correlations, age as covariate.
  4. Asymmetrical index = 2x [(L − R)/(L + R)].