Figure 4

Changes in cytokines and growth factors in CSF from ASD and CP patients after autologous BMMNC infusion. (A) Experiment design. CSF samples were collected from ASD and CP patients at day 0 as the baseline (before the first BMMNC infusion) and at day 150–360 (after the first BMMNC infusion and before the second BMMNC infusion) for CSF composition analysis by Luminex assay. (B) Graphs show the concentration of 27 analyzed molecules in the CSF from ASD and CP patients at baseline compared with those at 150–360 days after BMMNC infusion. Only samples in which cytokine concentration was detected by Luminex assay were included in the analysis. Groups were compared using paired T-test or Wilcoxon Signed Rank Test. Data were presented as Mean ± SEM for the concentration of indicated cytokines. Considered p-values were: *p < 0.05. p values > 0.05 are not shown.