Scientific Reports

Table 2 Statistical analysis of qMRI parameters fat fraction (FatFr), water-T2 mapping (T2), fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD) and λ1.

From: Muscle diffusion MRI reveals autophagic buildup in a mouse model for Pompe disease

Muscle	tp	FatFr		T2		FA			MD			RD			λ₁
		Anova		Anova		Anova		T-test	Anova		T-test	Anova		T-test	Anova
		F-val	p-val	F-val	p-val	F-val	p-val	p-val	F-val	p-val	p-val	F-val	p-val	p-val	F-val	p-val
Quadriceps	t0	3.00	0.09	0.00	0.95	9.80	< 0.01	0.458	3.53	0.06	-	7.19	0.01	0.074	0.17	0.68
	t1							0.002						< 0.001
	t2							< 0.001						< 0.001
	t3							< 0.001						0.003
	t4							0.003						< 0.001
	t5							< 0.001						< 0.001
	t6							0.001						< 0.001
	t7							< 0.001						< 0.001
Hamstrings	t0	0.67	0.42	0.53	0.47	14.53	< 0.01	0.131	6.58	0.01	0.296	12.13	< 0.01	0.137	0.17	0.68
	t1							0.108			< 0.001			< 0.001
	t2							0.007			< 0.001			< 0.001
	t3							0.003			0.005			< 0.001
	t4							< 0.001			0.005			< 0.001
	t5							< 0.001			< 0.001			< 0.001
	t6							0.002			< 0.001			0.001
	t7							< 0.001			0.002			< 0.001
Gastro. + Soleus	t0	0.01	0.92	0.00	0.98	7.49	0.01	0.319	7.50	0.01	0.810	9.41	< 0.01	0.593	3.19	0.08
	t1							0.010			< 0.001			< 0.001
	t2							< 0.001			< 0.001			< 0.001
	t3							0.002			0.011			0.006
	t4							0.004			0.002			0.002
	t5							0.021			0.005			0.008
	t6							< 0.001			< 0.001			< 0.001
	t7							< 0.001			0.002			< 0.001
Tibialis anterior	t0	0.00	0.97	0.03	0.86	13.61	< 0.01	0.041	11.48	< 0.01	0.574	16.95	< 0.01	0.273	3.43	0.07
	t1							< 0.001			< 0.001			< 0.001
	t2							0.002			< 0.001			< 0.001
	t3							< 0.001			0.009			< 0.001
	t4							< 0.001			< 0.001			< 0.001
	t5							0.014			0.026			0.022
	t6							< 0.001			< 0.001			< 0.001
	t7							< 0.001			< 0.001			< 0.001

When two-way ANOVA (timepoint, group) was significant, t-tests were carried out.

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