Table 4 Unadjusted and multivariable adjusted analyses of risk factors associated with HL.
Variables | Unadjusted analysis | Multivariable adjusted analysis | ||
|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
Age | 1.063 (1.033–1.094) |  < 0.001 | 1.070 (1.040–1.102) |  < 0.001 |
Sex | 1.044 (0.866–1.259) | 0.653 | – | – |
Craniofacial anomalies a | 13.021 (4.038–41.988) |  < 0.001 | 0.068 (0.021–0.221) |  < 0.001 |
NICU b | 0.403 (0.215–0.757) | 0.005 | 1.674 (0.824–3.400) | 0.154 |
Low birth weight c | 0.197 (0.155–0.699) | 0.012 | 4.537 (1.013–20.328) | 0.048 |
Mechanical ventilation d | 0.795 (0.229–2.755) | 0.717 | – | – |
HL-associated syndromes e | 5.603 (0.688–45.630) | 0.107 | – | – |
Hyperbilirubinemia f | 1.194 (0.199–7.165) | 0.846 | – | – |
Bacterial meningitis | 0.265 (0.267–2.548) | 0.25 | – | – |
In utero infection g |  > 999.99 (0.00– > 999.99) | 0.999 | – | – |
