Table 6 The result of the two-piecewise Cox proportional hazards regression model.

From: Association between high-density lipoprotein cholesterol and reversion to normoglycemia from prediabetes: an analysis based on data from a retrospective cohort study

Outcome: reversion to normoglycemia

All participants (HR, 95% CI, P)

Male

Female

Standard Cox regression

1.898 (1.758, 2.048) < 0.001

1.923 (1.753, 2.110) < 0.001

1.832 (1.597, 2.101) < 0.001

Fitting model by two-piecewise Cox proportional hazards regression

The inflection point of HDL-C

1.560

1.540

1.620

 ≤ inflection point

2.599 (2.289, 2.950) < 0.001

2.783 (2.373, 3.263) < 0.001

2.217 (1.802, 2.727) < 0.001

 > inflection point

1.103 (0.889, 1.368) 0.373

0.926 (0.666, 1.288) 0.648

1.266 (0.906, 1.770) 0.167

P for the log-likelihood ratio test

 < 0.001

 < 0.001

0.015

  1. Note 1: In all participants, we adjusted DBP, SBP, BMI, gender, age, drinking status, family history of diabetes, smoking status, FPG, AST, BUN, ALT, LDL-C, Scr, and TG.
  2. Note 2: For Male and Female subgroups, we adjusted for DBP, SBP, BMI, age, drinking status, family history of diabetes, smoking status, FPG, AST, BUN, ALT, LDL-C, Scr, and TG.
  3. HR hazard ratios, CI confidence, HDL-C high-density lipoprotein cholesterol.
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