Figure 7 | Scientific Reports

Figure 7

From: Identification of key pyroptosis-related genes and microimmune environment among peripheral arterial beds in atherosclerotic arteries

Figure 7

Hub genes and signature genes of pyroptosis and their correlations with immune and stromal cells. (a) PPI network of 50 pyroptosis-related genes in the PyroptosisScoreH cluster. (b) Ten hub genes in the PyroptosisScoreH cluster. (c) Signature gene selection by LASSO regression. (d) Comparison of expression levels of five genes (identified as both hub and signature genes) in the PyroptosisScoreH cluster and in the PyroptosisScoreL cluster. (e) Spearman correlation coefficients obtained from the correlations of GSDMD, CASP1, NLRC4, AIM2, and IL18 with the relative proportions of different types of immune cells.

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