Figure 3

Differences in tissue specific spectra stratified by known emission peaks for FAD, Bound NADH, and Free NADH comparing (a) healthy muscle, healthy bone, and aggregate spine tumor and (b) stratifying by tumor type. The x-axis represents fluorophore based on known emission of these compounds and the y-axis corresponds to the full width at half maximum (FWHM area). The cyan denotes healthy bone (N = 150), the dark blue represents healthy muscle (N = 111), pink corresponds to tumor (N = 74), purple is metastatic carcinoma (N = 57), and red is meningioma (N = 17). Bars represent minimum and maximum. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.