Table 4 Coded and natural variables and response results for the central composite design.
Standard order | Pressure (X1, bar) | Temperature (X2, °C) | Cosolvent (X3, %) | Naringenin (µg/g extract) |
|---|---|---|---|---|
1 | 200 (− 1) | 37 (− 1) | 5 (− 1) | 27,849.33 |
2 | 300 (1) | 37 (− 1) | 5 (− 1) | 27,733.86 |
3 | 200 (− 1) | 53 (1) | 5 (− 1) | 30,811.21 |
4 | 300 (1) | 53 (1) | 5 (− 1) | 24,591.80 |
5 | 200 (− 1) | 37 (− 1) | 15 (1) | 31,677.42 |
6 | 300 (1) | 37 (− 1) | 15 (1) | 34,237.62 |
7 | 200 (− 1) | 53 (1) | 15 (1) | 34,772.38 |
8 | 300 (1) | 53 (1) | 15 (1) | 39,104.50 |
9 | 165.9 (− 1.682) | 45 (0) | 10 (0) | 32,744.89 |
10 | 334.1 (1.682) | 45 (0) | 10 (0) | 40,032.23 |
11 | 250 (0) | 31.5 (− 1.682) | 10 (0) | 26,638.12 |
12 | 250 (0) | 58.4 (1.682) | 10 (0) | 49,163.31 |
13 | 250 (0) | 45 (0) | 1.6 (− 1.682) | 7460.86 |
14 | 250 (0) | 45 (0) | 18.4 (1.682) | 36,552.03 |
15 | 250 (0) | 45 (0) | 10 (0) | 36,074.36 |
16 | 250 (0) | 45 (0) | 10 (0) | 40,344.00 |
17 | 250 (0) | 45 (0) | 10 (0) | 37,395.23 |
18 | 250 (0) | 45 (0) | 10 (0) | 36,611.09 |
19 | 250 (0) | 45 (0) | 10 (0) | 43,603.19 |
20 | 250 (0) | 45 (0) | 10 (0) | 41,637.04 |
