Table 2 Multivariate logistic regression of factors associated with chemotherapy among MpBC.
From: Chemotherapy is of prognostic significance to metaplastic breast cancer
Factors | One-way logistic regression | Multivariate logistic regression | ||||
---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |
Year of diagnosis | 1.052 | 0.997–1.109 | 0.064 |  |  |  |
Age | ||||||
  ≤ 60y vs. > 60y | 4.319 | 3.268–5.709 |  < 0.001 | 4.100 | 3.052–5.509 |  < 0.001 |
Race | Â | Â | 0.002 | Â | Â | 0.237 |
 Black vs. white | 1.979 | 1.340–2.922 | 0.001 | 1.423 | 0.930–2.180 | 0.104 |
 Others* vs. white | 1.348 | 0.821–2.215 | 0.238 | 1.202 | 0.695–2.077 | 0.510 |
Histologic grade |  |  |  < 0.001 |  |  | 0.001 |
 II vs. I | 2.886 | 1.153–5.504 | 0.001 | 3.361 | 1.658–6.815 | 0.001 |
 III vs. I | 5.008 | 2.815–8.910 |  < 0.001 | 4.685 | 2.462–8.913 |  < 0.001 |
Stage | Â | Â | 0.001 | Â | Â | 0.014 |
 II vs. I | 1.510 | 1.139–2.003 | 0.004 | 1.539 | 1.114–2.126 | 0.009 |
 III vs. I | 2.231 | 1.430–3.480 |  < 0.001 | 1.792 | 1.099–2.921 | 0.019 |
Radiation therapy | ||||||
 Yes vs. no or unknown | 2.682 | 2.070–3.475 |  < 0.001 | 2.710 | 2.041–3.599 |  < 0.001 |
Surgery | ||||||
 BCS vs. mastectomy | 1.053 | 0.821–1.351 | 0.684 |  |  |  |
Subtype | Â | Â | 0.031 | Â | Â | 0.323 |
 HR–/HER2 + vs. TNBC | 2.008 | 0.957–4.211 | 0.065 | 1.596 | 0.725–3.515 | 0.246 |
 HR + /HER2 + vs. TNBC | 4.517 | 1.045–19.533 | 0.044 | 3.136 | 0.666–14.772 | 0.148 |
 HR + /HER2– vs. TNBC | 1.262 | 0.933–1.707 | 0.132 | 1.099 | 0.785–1.538 | 0.582 |