Table 1 Demographics and clinicopathological characteristics of patients (n = 111).
Characteristics | Number of patients (%) |
|---|---|
Gender | |
 Male | 89 (80.2%) |
 Female | 22 (19.8%) |
Age | |
 ≤ 63 | 63 (56.8%) |
 > 63 | 48 (43.2%) |
Smoking status | |
 Never-smokers | 68 (61.3%) |
 Former or current smokers | 43 (38.7%) |
Histological subtype | |
 Adenocarcinoma | 70 (63.1%) |
 Squamous carcinoma | 41 (36.9%) |
Clinical stage at ICI rechallenge initiation | |
 IIIB–C | 13 (11.7%) |
 IV | 98 (88.3%) |
PD-L1 expression | |
 Number tested | 47 (42.3%) |
 TPS < 1% | 20/47 (53.3%) |
 1% ≤ TPS < 50% | 9/47 (19.1%) |
 TPS ≥ 50% | 18/47 (38.3%) |
 Unknown | 64 (57.7%) |
Driver genes | |
 Number tested | 71 (64.0%) |
 Negative | 37/71 (52.1%) |
 Sensitive mutations | 28/71 (39.4%) |
 Wildtype | 6/71 (8.5%) |
 Unknown | 40 (36.0%) |
M Staging at ICI rechallenge initiation | |
 0 | 16 (14.4%) |
 1a | 25 (22.5%) |
 1b | 33 (29.7%) |
 1c | 37 (33.3%) |
Metastatic sites at ICI rechallenge initiation | |
 Brain | 33(29.7%) |
 Liver | 15(13.5%) |
 Bone | 43(38.7%) |
