Figure 2
From: microRNA blood signature for localized radiation injury
Injury follow-up. (A) Kinetics of the observational injury score. Box plots show the mean score from two experimenters for each group of doses at D7 (a) D10 (b) and D14 (c) post-irradiation. (d) Representative pictures of irradiated limb after 7, 10 and 14 days post-irradiation for each irradiated group (same mouse is represented for each group at each time point). (B) Monitoring of the cutaneous blood perfusion. Graphs show the mean ratio of the blood flow of the irradiated limb over the contralateral, non-irradiated one (IRR/NIR) at D7 (a), D10 (b) and D14 (c) post-irradiation. Representative Doppler scans of each dose group at day 14 post-irradiation are showed (d), with the area used for the analysis delimited in black. N = 15 for control, 20 and 80 Gy groups, N = 10 for 40 Gy group. Kruskal–Wallis test, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.
