Figure 4 | Scientific Reports

Figure 4

From: Bioinformatics analysis identifies coagulation factor II receptor as a potential biomarker in stomach adenocarcinoma

Figure 4

Screening the upstream miRNA and lncRNA of F2R and constructing the ceRNA network diagram. (A) Network mapping of F2R-related miRNAs based on the Starbase database. (B) The expression of F2R based on the TCGA dataset was negatively correlated with the expression of hsa-miR-144-5p and hsa-miR-486-5p. (C) The expression of hsa-miR-144-5p and hsa-miR-486-5p in STAD tissues based on the TCGA data set decreased. (D) Mapping of hsa-miR-144-5p and hsa-miR-486-5p related lncRNA networks based on the Starbase database. (E) To construct an F2R-centered ceRNA network. (F) Based on the TCGA data set, the expression of hsa-miR-144-5p was negatively correlated with the expression of FTX, and the expression of has-miR-486-5p was negatively correlated with the expression of ZEB1-AS1. (G) The expression of FTX and ZEB1-AS1 in STAD based on the TCGA data set increased. (H) Based on the TCGA data set, F2R expression was positively correlated with FTX and ZEB1-AS1 expression.

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